Perampanel

Fycompa

癲控達膜衣錠

2mg/FC tab

12. NEUROLOGY; ;

12.02. ADJUVANT ANTICONVULSANTS;;

AMPA Glutamate Receptor Antagonist

4歲以上局部癲癇發作併有或未併有續發型全身發作之治療
7歲以上原發型全身性強直陣攣癲癇發作併有原發性全身發作之輔助治療

Unknown

Unknown

PO
Partial-onset seizures
≧12years adolescents and adult: Initial 2 mg once daily at bedtime; may increase daily dose by 2 mg once daily no more frequently than at weekly intervals based on response and tolerability. Recommended maintenance dose: 8 to 12 mg once daily at bedtime.
Children 4-11 years:
BW≧30kg: Initial 2 mg/day orally taken at bedtime. May increase in 2 mg/day increments no more frequently than at weekly intervals. Maintenance 4-8 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 2 mg/day increments at weekly intervals up to 12 mg orally once daily.
BW 20 to <30kg: Initial 1 mg/day orally taken at bedtime. May increase in 1 mg/day increments no more frequently than at weekly intervals. Maintenance 4-6 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 1 mg/day increments at weekly intervals up to 8 mg orally once daily.
BW < 20kg: Initial 1 mg/day orally taken at bedtime. May increase in 1 mg/day increments no more frequently than at weekly intervals. Maintenance 2-4 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 0.5 mg/day increments at weekly intervals up to 6 mg orally once daily.

Primary generalized tonic-clonic seizures (adjunct)
≧12years adolescents and adult: Initial 2 mg once daily at bedtime; may increase dose by 2 mg once daily no more frequently than at weekly intervals based on response and tolerability. Recommended maintenance dose: 8 mg once daily at bedtime; if tolerated and further seizure control is needed, may increase up to 12 mg once daily.
Children 7-11 years:
BW≧30kg: Initial 2 mg/day orally taken at bedtime. May increase in 2 mg/day increments no more frequently than at weekly intervals. Maintenance 4-8 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 2 mg/day increments at weekly intervals up to 12 mg orally once daily.
BW 20 to <30kg: Initial 1 mg/day orally taken at bedtime. May increase in 1 mg/day increments no more frequently than at weekly intervals. Maintenance 4-6 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 1 mg/day increments at weekly intervals up to 8 mg orally once daily.
BW < 20kg: Initial 1 mg/day orally taken at bedtime. May increase in 1 mg/day increments no more frequently than at weekly intervals. Maintenance 2-4 mg orally once daily at bedtime. If tolerated and further seizure control is needed, may increase by 0.5 mg/day increments at weekly intervals up to 6 mg orally once daily.

Dizziness, drowsiness, vertigo, aggressive behavior, abnormal gait

1.停用時應逐漸減低劑量
2.本品不可咀嚼、壓碎或剝半
3.可能引起頭暈、嗜睡，建議不要駕駛、操作複雜機器或從事其他危險性活動
4.本品含lactose，乳糖不耐受症(lactose intolerance)不建議使用

服藥期間需避免併用酒精性飲料

建立者

103617

建立時間

2018-09-18 10:54:05

維護者

103617

維護時間

2022-04-27 14:45:38