用法用量 |
Anemia due to chronic kidney disease
ON dialysis: SC 20 to 50 units/kg 3 times per week ; in some patients with lower initial Hb levels (eg, <8 g/dL), an initial dose of up to 100 units/kg 3 times per week may be considered
NOT on dialysis: SC (preferred route) 50 to 100 units/kg every 1 to 2 weeks; typical initial regimens include 4,000 to 10,000 units once weekly or 10,000 to 20,000 units every other week
Anemia due to chemotherapy in cancer patients
SC Initial dose 150 units/kg 3 times a week or 40,000 units once weekly until completion of chemotherapy.
Reduction of allogenic blood transfusion in anemic surgery
SC 300 units/kg/day for 15 days total, beginning 10 days before surgery, on the day of surgery, and for 4 days after surgery or 600 units/kg once weekly for 4 doses, given 21-, 14-, and 7 days before surgery, and on the day of surgery. |