Carfilzomib

Kyprolis

凱博斯凍晶注射劑

30mg/vial

09. HEMATOLOGY; ;

09.09. THROMBOLYTIC AGENTS;;

Antineoplastic Agent, Proteasome Inhibitor

標靶藥物

X 動物或人體的試驗中或使用經驗發現對胎兒有害，而造成的傷害明顯大於可能的益處。

Unknown

IVF/IVD
Multiple myeloma, relapsed/refractory (single-agent; 20/27 mg/m2 regimen)
Cycle 1: 20 mg/m2 over 10 minutes on days 1 and 2; if tolerated, increase dose to 27 mg/m2 over 10 minutes on days 8, 9, 15, and 16 of a 28-day treatment cycle.
Cycles 2 to 12: 27 mg/m2 over 10 minutes on days 1, 2, 8, 9, 15, and 16 of a 28-day treatment cycle.
Cycle 13 and beyond: IV: 27 mg/m2 over 10 minutes on days 1, 2, 15, and 16 of a 28-day treatment cycle; continue until disease progression or unacceptable toxicity.
Multiple myeloma, relapsed/refractory (single-agent; 20/56 mg/m2 regimen)
Cycle 1: IV: 20 mg/m2 over 30 minutes on days 1 and 2; if tolerated, increase dose to 56 mg/m2 over 30 minutes on days 8, 9, 15, and 16 of a 28-day treatment cycle.
Cycles 2 to 12: IV: 56 mg/m2 over 30 minutes on days 1, 2, 8, 9, 15, and 16 of a 28-day treatment cycle.
Cycle 13 and beyond: IV: 56 mg/m2 over 30 minutes on days 1, 2, 15, and 16 of a 28-day treatment cycle; continue until disease progression or unacceptable toxicity.

Anemia, fatigue, nausea, dyspnea, thrombocytopenia

1.應於2-8℃冷藏儲存
2.藥品配製：
(1)將15ml注射用水緩慢沿著注射瓶內壁加入注射小瓶中。
(2)輕輕旋轉或上下緩慢反轉約1分鐘或直到內容物溶解為止，勿大力搖晃以免起泡。若出現泡沫需靜置約5分鐘直到泡沫消失。
(3)可直接靜脈給藥或以50-100ml的5%Dextrose稀釋後靜脈輸注。
(4)溶解後之注射小瓶僅限單次使用，未用完部分應丟棄
3.可能引起疲勞、頭暈、昏倒及/或血壓降低副作用。出現這些症狀時，不可駕駛或操作機械

建立者

103617

建立時間

2021-09-07 12:18:28

維護者

103617

維護時間

2021-09-13 09:50:38