Antithymocyte immunoglobulin (rabbit)

Thymoglobuline

兔抗胸腺細胞免疫球蛋白

25mg/5ml/vial

05. BIOLOGIC AND IMMUNOLOGIC AGENTS; ;

05.04. IMMUNE GLOBULINS;;

Transplant rejection

預防及治療移植物之排斥，嚴重再生不良性貧血

C 動物試驗顯示有致畸胎的結果，但沒有針對孕婦或動物有對照組的研究可證明其危險性。

Unknown

IVF (infusion rate ≧ 4hrs)
Transplant rejection
Prophylaxis of acute graft rejection
1-1.5mg/kg/day for 2-9 days after transplantation of kidney, pancreas or liver.
1-1.5mg/kg/day for 5 days after heart transplantation.
Treatment of acute graft rejection
1.5mg/kg/day for 3-14 days.
Prophylaxis of acute and chronic graft versus host disease
2.5mg/kg/day 由移植前4天至移植前2或1天
Treatment of steroid-resistant, acute graft versus host disease
劑量依個體而定，usually between 2-5mg/kg/day for 5days
Aplastic anemia
2.5-3.5mg/kg/day for 5 consecutive days.

Abdominal pain, diarrhea, nausea, vomiting, myalgia, headache, hypertension, peripheral edema, shivering, leukopenia, thrombocytopenia, fever.

1.活動性、急性或慢性感染者應避免進行任何免疫抑制療程。
2.對兔子蛋白成分過敏者。

1.以N/S或D5W稀釋後，最好以高流量之大靜脈行靜脈注射，輸注時建議以內置0.22mcg濾器的注射管線給藥。
2.輸注前一小時可先給予全身性抗組織胺或類固醇，並避免輸注時間少於4小時，以預防無防禦性過敏反應。
3.2.本品乾粉以5ml Dis-water溶解(請立即稀釋)，以0.9% NS或D5W稀釋，使輸注溶液體積達50-500ml (通常50ml/vial)。
3.稀釋後於2-8℃可存放24小時。
3.Monitoring Parameters: lymphocyte profile, CBC with differential and platelet count, vital signs during administration

建立者

100348

建立時間

2009-08-11 08:29:36

維護者

103617

維護時間

2024-01-24 08:25:37